Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives
Osteogenesis imperfecta is an inherited connective tissue disorder with wide phenotypic and molecular heterogeneity.A common issue associated with the molecular abnormality is a disturbance in bone Sports Bra matrix synthesis and homeostasis inducing bone fragility.In very early life, this can lead to multiple fractures and progressive bone deformi